Ciprofloxacin hydrochloride hydrate CAS NO.86393-32-0

Ciprofloxacin Hydrochloride

[Chemical Name]

1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid·Hydrochloride·Monohydrate

[Structure Formula]

[Molecular Formula]

C17H18FN3O3·HCl·H2O

[Molecular Weight]

385.81

[Specification]

USP32, EP6, BP2010

[Uses]

It is a broad-spectrum antibiotic of high efficacy

Items of Test

Standard

Result of Test

Appearance

White or light yellow crystalline powder

conform

Identification

(a)   IR

(b)   TLC

(c) the reaction of chloride

IR spectrum of sample corresponds to that of reference standard.

The intensity and RF value of the principal band obtained from the test solution corresponds to that obtained from the standard solution.

A solution of IIresponds to the tests of chloride

Conform

Conform

Conform

Related substances HPLC

Chromatographic purity ≤ 0.2%

Ciprofloxacin ethylenediamine analog ≤ 0.2%

Unspecified impurity ≤ 0.50%

Total impurities ≤ 0.5%

0.15%

<0.11%

0.40%

Ph

3.0-4.5

3.7

Heavy metals

≤20ppm

<20ppm

Fluoroquinolonic acid

≤0.2%

Conform

Sulphated ash

≤0.04%

<0.04%

Water

4.7%-6.7%

5.90%

Residue of ignition

≤0.1%

0.05%

Residual solvent

ethanol ≤ 5000ppm

Isoamyl alcohol≤ 4000ppm

560ppm

Not found  

Assay (HPLC)

98.0%-102%

99.8%